BRL News:
« Genome Portrait of MCF-7 in NYT, Genome Res. »
A map of breakpoints in the MCF-7 breast cancer cell line made by
BRL grad student Oliver A. Hampton is featured in The New York Times
("The Chaos Inside a Cancer Cell")
and is published in Genome Research (Hampton et al., 2008).
« Pash » A new version of Pash, 2.0, has been released! It improves mapping accuracy in the presence of indels,
increases speed by up to a factor of 3 over the previous version, and provides the option of refining Pash anchorings by performing banded alignment.
Contributed by Pash's main developer, Cristian Coarfa. Please see the license and download page to acquire the new version.
« Genomic Triangulation » Our paper
Human-Specific Changes of Genome Structure Detected by Genomic Triangulation
as well our contributions to the
Evolutionary and Biomedical Insights from the Rhesus Macaque Genome paper
have been published.
Data used in the ancestral reconstructions, including genome pairwise comparisons, BAC mappings, fosmid mappings, and markers, as well as the reconstructions themselves and
detected breakpoints are available through
Genboree.
« Pash » A new version of Pash has been released!
Improvements in usage, dependencies, accuracy, scratch space, and small-query mapping; also, the introduction of new scoring methods. Contributed by Pash's main developer,
Cristian Coarfa. Please see the license and download page to acquire the new version.
« H.s. Chr3 & Chr12 » The Human Chr 3 & 12 Nature
articles have been published. Figure 2 in both papers were contributed by
Alan Harris. See the
Genboree news items for more information and links.
« Gap Map » We applied the Gap Map concept to the Rhesus-Human Comparative Linkage Map.
« Rhesus » Our integrated comparative map of rhesus, chimp, and human
includes
matepair chains,
contigs,
and
our latest mappings
of
16,495 Rhesus BACs to the Human genome using the
PGI method.
Note: The rhesus PGI paper
has been published in Genome Research!
« Sequencing » We have developed the Tagamizer program to parse and identify short sequence
tags present in a sequencing read. The Tagamizer program is now
available for download.